Factors Associated With Prolonged Respiratory Virus Detection From Polymerase Chain Reaction of Nasal Specimens Collected Longitudinally in Healthy Children in a US Birth Cohort.

Zheyi Teoh Shannon C ConreyMonica McNealAllison BurrellRachel M BurkeClaire P MattisonMeredith L McMorrow Natalie J Thornburg Daniel C PayneArdythe L MorrowMary Allen Staat

Published in: Journal of the Pediatric Infectious Diseases Society (2024)

Prolonged virus detection was observed in 1 in 4 viral infections in this cohort of healthy children and varied by pathogen, occurring most often for bocavirus and rhinovirus/enterovirus. Evaluating the immunological basis of how viral co-detections and recurrent viral infections impact duration of virus detection by PCR is needed to better understand the dynamics of prolonged viral shedding.

Keyphrases

sars cov
real time pcr
loop mediated isothermal amplification
young adults
label free
candida albicans
disease virus
sensitive detection
chronic rhinosinusitis