Heart failure development in obesity: underlying risk factors and mechanistic pathways.
Shabbar JamalyLena M S CarlssonMarkku PeltonenJohanna C Andersson AssarssonKristjan KarasonPublished in: ESC heart failure (2020)
Both atrial fibrillation and myocardial infarction as time-dependent variables were independently and strongly related to incident HF in people with excess body fat, suggesting two main obesity-related mechanistic pathways leading to either HFpEF or HFrEF.
Keyphrases
- heart failure
- atrial fibrillation
- risk factors
- insulin resistance
- metabolic syndrome
- weight loss
- type diabetes
- high fat diet induced
- left ventricular
- weight gain
- acute heart failure
- cardiovascular disease
- left atrial
- percutaneous coronary intervention
- adipose tissue
- left atrial appendage
- physical activity
- catheter ablation
- direct oral anticoagulants
- drug induced
- mitral valve