Cannabis use is both independently associated with and mediates worse psychosocial health in patients with epilepsy.
Sandra WahbyVikram KarnikAnita BrobbeySamuel WiebeTolulope SajobiColin Bruce JosephsonPublished in: Journal of neurology, neurosurgery, and psychiatry (2019)
There is a strong and independent association between cannabis use and poor psychosocial health, and it partially mediates the deleterious effect of a psychiatric history on these same outcomes. Inclusion of PROMs in future cannabis trials is warranted.