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Ezetimibe Prevents Ischemia/Reperfusion-Induced Oxidative Stress and Up-Regulates Nrf2/ARE and UPR Signaling Pathways.

Denise PesericoChiara StranieriUlisse GarbinChiara Mozzini CElisa DaneseLuciano CominaciniAnna Maria Fratta Pasini
Published in: Antioxidants (Basel, Switzerland) (2020)
Ezetimibe counteracts IR-induced oxidative stress and induces Nrf2 and UPR pathway activation.
Keyphrases
  • hydrogen peroxide
  • oxidative stress
  • signaling pathway
  • pi k akt
  • mouse model
  • epithelial mesenchymal transition
  • induced apoptosis
  • endoplasmic reticulum stress