Local vancomycin therapy to reduce surgical site infection in adult spine surgery: a randomized prospective study.
Sohrab SalimiHamid Reza Khayat KashaniShirzad AzhariSohrab SadeghiSiavash SheikhghomyPoorya ParyanMaryam KhayatKashaniPublished in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2021)
Intra-wound vancomycin has no effect on SSI; in addition, it can increase the rate of gram-negative infections.