CTXP, The Major Cobra Toxin Peptide From Naja Naja Oxiana Venom; A Promising Target for Antivenom Agent Development.
Mohammad Hosseininejad ChafiMohsen Eslamnezhad-NaminMansoureh Shahbazi DastjerdehMohammad Reza ZareinejadAkbar OghalaieKamran Pooshang BagheriFatemeh Kazemi-LomedashtGholamreza KarimiMehdi Razzaghi-AbyanehSima Sadat SeyedjavadiMahdi BehdaniPublished in: Current protein & peptide science (2024)
Surprisingly, the Anti-CTXP antibody could neutralize 8-LD50 of the CTXP peptide. These results identified CTXP (a 7 kDa peptide) as a potential target for the development of novel efficient antivenom agents.