Quercetin sensitizes human myeloid leukemia KG-1 cells against TRAIL-induced apoptosis.
Adel NaimiAtefeh EntezariMajid Farshdousti HaghAli HassanzadehRaedeh SaraeiSaeed SolaliPublished in: Journal of cellular physiology (2018)
Our findings suggest that QUR can sensitize the acute myeloid KG-1 cells against TRAIL. Moreover, the combinational therapy of these agents might promisingly improve the clinical efficacy of TRAIL in patients with AML.
Keyphrases
- induced apoptosis
- endoplasmic reticulum stress
- signaling pathway
- oxidative stress
- acute myeloid leukemia
- bone marrow
- dendritic cells
- endothelial cells
- liver failure
- cell cycle arrest
- stem cells
- intensive care unit
- cell death
- drug induced
- cell proliferation
- acute lymphoblastic leukemia
- induced pluripotent stem cells