Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability.
Pierre-Louis HollierCandice ChapoulyAissata DiopSarah GuimbalLauriane CornuaultAlain-Pierre GadeauMarie-Ange RenaultPublished in: Cardiovascular research (2022)
The present study highlights for the first time that FL-Dhh and N-Hh ligands have antagonistic properties especially in ECs.
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