Identifying signals of potentially harmful medications in pregnancy: use of the double false discovery rate method to adjust for multiple testing.
Alana Y CavadinoDavid Prieto-MerinoJoan K MorrisPublished in: British journal of clinical pharmacology (2018)
The double FDR method appears to improve the detection of potential teratogens in comparison to the single FDR, while maintaining a low risk of false positives. Use of double FDR is recommended in routine signal detection analyses of CA data.