Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets.

Qiufang ZongHuan QuYahui ZhaoHaoyu LiuShenglong WuShuai WangWenbin BaoDemin Cai

Published in: Journal of animal science and biotechnology (2022)

Collectively, our results demonstrate the utility of the natural product NaBu as a potential anti-mycotoxin nutritional strategy for regulating cholesterol metabolism via RORγ-mediated histone acetylation modification.

Keyphrases

dna methylation
low density lipoprotein
oxidative stress
diabetic rats
histone deacetylase
mechanical ventilation
gene expression
mouse model
drug induced
climate change
human health
risk assessment