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Bayesian predictive model to assess BRCA2 mutational status according to clinical history: Early onset, metastatic phenotype or family history of breast/ovary cancer.

Priscilla LeonGeraldine Cancel-TassinViolaine BourdonBruno BuecherStephane OudardLaurent BrureauLionel JouffePascal BlanchetDominique Stoppa-LyonnetFlorence CouletHagay SobolOlivier Cussenot
Published in: The Prostate (2021)
Our results showed that a higher frequency of BRCA2 mutation carriers is observed, not only among PrCa patients with young onset or a metastatic disease, but also with a personal or a familial history of breast cancer.
Keyphrases
  • early onset
  • late onset
  • squamous cell carcinoma
  • small cell lung cancer
  • breast cancer risk
  • papillary thyroid
  • squamous cell
  • childhood cancer
  • lymph node metastasis
  • middle aged