Nabiximols discontinuation rate in a large population of patients with multiple sclerosis: a 18-month multicentre study.

Clara Grazia ChisariClaudio SolaroPasquale AnnunziataRoberto BergamaschiAssunta BiancoSimona BonavitaVincenzo Brescia MorraRoberto Bruno BossioElisabetta CapelloLetizia CastelliPaola CavallaGianfranco CostantinoDiego CentonzeSalvatore CottoneMaura Chiara DanniFederica EspositoAlberto GajofattoClaudio GasperiniAngelica GuareschiRoberta LanzilloGiacomo LusGiorgia Teresa ManiscalcoManuela MattaDamiano PaolicelliLoredana PetrucciSimona PontecorvoIsabella RighiniMarco RovarisEdoardo SessaGabriella SpinicciDaniele SpitaleriPaola ValentinoMauro ZaffaroniMario ZappiaFrancesco Patti

Published in: Journal of neurology, neurosurgery, and psychiatry (2020)

THC:CBD effects were sustained for 18 months with a relatively stable number of puffs per day. About 50% of patients abandoned THC:CBD therapy for loss of efficacy or adverse events.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
patient reported