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Regulatory miR-SNP rs4636297A > G in miR-126 is linked to increased risk of rigidity feature in patients with Parkinson's disease.

Sheyda PooshaniAbbas AzadmehrPayam SaadatMahdi SepidarkishAbdolreza Daraei
Published in: The International journal of neuroscience (2024)
We report for the first time a significant association of functional regulatory SNP rs4636297A > G in the miR-126 with the Parkinson's clinicopathology. Therefore, this miR-SNP can have a potential predictive biomarker capacity for rigidity in PD, although this hypothesis needs further investigation in the future.
Keyphrases
  • cell proliferation
  • long non coding rna
  • long noncoding rna
  • genome wide
  • machine learning
  • high density
  • risk assessment
  • current status