What is the exact working mechanism of botulinum toxin A and sacral nerve stimulation in the treatment of overactive bladder/detrusor overactivity? ICI-RS 2017.

Sachin MaldeChristopher FryBrigitte Schurch T A T Marcelissen Marcio Augusto AverbeckAlex DigesuArun Sahai

Published in: Neurourology and urodynamics (2019)

The working mechanism of BTX-A and SNS is complex. The exact mechanisms are still unknown, although considerable progress has been made in our understanding. Further research proposals are suggested to help further elucidate these mechanisms.

Keyphrases

botulinum toxin
density functional theory
molecular dynamics
replacement therapy