Enterobacter cloacae Complex Sequence Type 171 Isolates Expressing KPC-4 Carbapenemase Recovered from Canine Patients in Ohio.
Joshua B DanielsLiang ChenSusan V GrootersDixie F MollenkopfDimitria A MathysPreeti PancholiBarry N KreiswirthThomas E WittumPublished in: Antimicrobial agents and chemotherapy (2018)
Companion animals are likely relevant in the transmission of antimicrobial-resistant bacteria. Enterobacter xiangfangensis sequence type 171 (ST171), a clone that has been implicated in clusters of infections in humans, was isolated from two dogs with clinical disease in Ohio. The canine isolates contained IncHI2 plasmids encoding bla KPC-4 Whole-genome sequencing was used to put the canine isolates in phylogenetic context with available human ST171 sequences, as well as to characterize their bla KPC-4 plasmids.
Keyphrases
- klebsiella pneumoniae
- multidrug resistant
- escherichia coli
- genetic diversity
- end stage renal disease
- newly diagnosed
- ejection fraction
- endothelial cells
- chronic kidney disease
- prognostic factors
- staphylococcus aureus
- acinetobacter baumannii
- peritoneal dialysis
- patient reported outcomes
- induced pluripotent stem cells
- cystic fibrosis
- amino acid