Genome-wide association studies on Northern Italy isolated populations provide further support concerning genetic susceptibility for major depressive disorder.
Vincenzo DattiloSheila UliviAlessandra MinelliMartina La BiancaEdoardo GiacopuzziMarco BortolomasiStefano BignottiMassimo GennarelliPaolo GaspariniMaria Pina ConcasPublished in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2022)
Our work suggests new possible genes associated with MDD, and the PRS analysis confirms the polygenic nature of this disorder. Future studies are required to better understand the role of these findings in MDD.