High frequency of increased triclosan MIC among CC5 MRSA and risk of misclassification of the SCCmec into types.
Alice Slotfeldt VianaAna Maria Nunes BotelhoAndries FederAhmed Magdi MoustafaDeborah Nascimento Santos SilvaCaroline Lopes MartiniAdriana Lucia Pires FerreiraMaria Cícera Silva-CarvalhoBernadete Teixeira Ferreira-CarvalhoPaul Joseph PlanetAgnes Marie Sá FigueiredoPublished in: The Journal of antimicrobial chemotherapy (2022)
Our work highlights an important misclassification problem of SCCmecII in isolates harbouring TnSha1 when Boye's method is used for typing, which could have important implications for molecular epidemiology of MRSA. The importance of increased-MIC phenotype is still a matter of controversy that deserves more study given the widespread use of triclosan in many countries. Our results suggest expanding prevalence that may indicate strong selection for this phenotype.