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Evaluation of Vancomycin Area Under the Concentration-Time Curve Predictive Performance Using Bayesian Modeling Software With and Without Peak Concentration: An Academic Hospital Experience for Adult Patients Without Renal Impairment.

Hyun-Ki KimTae-Dong Jeong
Published in: Annals of laboratory medicine (2023)
The usefulness of the peak concentration for predicting the AUC on the next occasion by Bayesian modeling was not demonstrated; therefore, the practical value of peak sampling for AUC-guided dosing can be questioned. As this study was conducted in a specific setting and generalization is limited, results should be interpreted cautiously.
Keyphrases
  • healthcare
  • methicillin resistant staphylococcus aureus
  • adverse drug
  • drug induced