Concentration-dependent effect of bleaching agents on the immunolabelling of interleukin-6, interleukin-17 and CD5-positive cells in the dental pulp.

Francine Benetti João Eduardo Gomes-FilhoL L FerreiraG Sivieri-AraújoE ErvolinoA L F BrisoLuciano Tavares Angelo Cintra

Published in: International endodontic journal (2018)

IL-6 and IL-17 participated in inflammation in the pulp tissue of rats after tooth bleaching, particularly at 2 days. The immunolabelling was greater with increasing H2 O2 concentration. This process was accompanied by the prolonged activation of CD5-positive cells.

Keyphrases

induced apoptosis
cell cycle arrest
hydrogen peroxide
oxidative stress
endoplasmic reticulum stress
signaling pathway
cell death
nk cells
pi k akt