Next-generation sequencing confirms T-cell clonality in a subset of pediatric pityriasis lichenoides.
Shyam Sampath RaghavanJennifer Y WangAlejandro A GruAnn L MarquelingJoyce M C TengRyanne A BrownRoberto A NovoaYoun KimJames ZehnderBing Melody ZhangKerri E RiegerPublished in: Journal of cutaneous pathology (2021)
T-cell clonality is a common finding in PL, probably representing a "reactive clonality" rather than a true lymphoproliferative disorder. Clonality alone cannot be used as a means to distinguish PL from lymphomatoid papulosis or cutaneous lymphoma.