Small Molecule-mediated Disruption of Ribosome Biogenesis Synergizes With FGFR Inhibitors to Suppress Glioma Cell Growth.
Asimina ZisiDimitris C KanellisSimon MoussaudIda KarlssonHelena CarénLars BräutigamJiri BartekMikael S LindströmPublished in: Neuro-oncology (2022)
This study conceptualizes the implementation of RiBi inhibition as a viable future therapeutic strategy for glioma and reveals an FGFR connection to the cellular response upon RiBi inhibition with potential translational value.