Heart failure and chronic kidney disease manifestation and mortality risk associations in type 2 diabetes: A large multinational cohort study.
Kåre Inge BirkelandJohan BodegardJan W ErikssonAnna NorhammarHermann HallerGerard C M LinssenAmitava BanerjeeMarcus ThuressonSuguru OkamiElena Garal-PantalerJetty A OverbeekJil Billy MamzaRuiqi ZhangToshitaka YajimaIssei KomuroTakashi KadowakiPublished in: Diabetes, obesity & metabolism (2020)
In a large multinational study of >750 000 CVRD-free patients with T2D, HF and CKD were consistently the most frequent first cardiovascular disease manifestations and were also associated with increased mortality risks. These novel findings show these cardiorenal diseases to be important and serious complications requiring improved preventive strategies.