Survival and Neurologic Outcomes From Pharmacologic Peptide Administration During Cardiopulmonary Resuscitation of Pulseless Electrical Activity.
Matt T OberdierJing LiDaniel I AmbinderMasahito SuzukiEthan TumarkinSarah FinkLuca NeriXiangdong ZhuCody N JusticeTerry L Vanden HoekHenry R HalperinPublished in: Journal of the American Heart Association (2024)
TAT-PHLPP9c resulted in improved survival with full neurologic function after sudden cardiac arrest in a swine model of pulseless electrical activity, and the peptide shows potential as an intra-CPR pharmacologic agent.