Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene.

Riccardo MasettiSalvatore Nicola BertuccioAnnalisa AstolfiFrancesca ChiariniAnnalisa LonettiValentina IndioMatilde De LucaJessica BandiniSalvatore SerravalleMonica FranzoniMartina PigazziAlberto Maria MartelliGiuseppe BassoFranco LocatelliAndrea Pession

Published in: Journal of hematology & oncology (2017)

Our findings indicate that the GLI inhibitor GANT61 may be used to specifically target the CBFA2T3-GLIS2 fusion gene in pediatric AML.

Keyphrases

copy number
genome wide
acute myeloid leukemia
genome wide identification
gene expression
dna methylation