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Development of a Pipeline for Adverse Drug Reaction Identification in Clinical Notes: Word Embedding Models and String Matching.

Klaske R SiegersmaMaxime EversSophie Heleen BotsFloor GroepenhoffYolande AppelmanLeonard HofstraIgor I TulevskiG Aernout SomsenHester M den RuijterMarco René SpruitN Charlotte Onland-Moret
Published in: JMIR medical informatics (2022)
The ADRIN method and prototype are effective in recognizing ADRs in Dutch clinical notes from cardiac diagnostic screening centers. Surprisingly, incorporation of the MedDRA did not result in improved identification on top of word embedding models. The implementation of the ADRIN tool may help increase the identification of ADRs, resulting in better care and saving substantial health care costs.
Keyphrases
  • healthcare
  • adverse drug
  • bioinformatics analysis
  • quality improvement
  • palliative care
  • emergency department
  • heart failure
  • pain management
  • chronic pain
  • atrial fibrillation
  • health insurance