Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ42.
Seong Soo A AnByoung-Sub LeeJi Sun YuKuntaek LimGwang Je KimRyan LeeSang Yun KimSungmin KangYoung Ho ParkMin Jeong WangYoung Soon YangYoung Chul YounSangYun KimPublished in: Alzheimer's research & therapy (2017)
Synthetic Aβ spiked into the blood plasma of patients with AD, but that of not elderly normal control subjects, induced dynamic changes in the formation of AβOs over time. AβOs were detected by the MDS, which is a useful blood-based assay with high sensitivity and specificity for AD diagnosis.