Implanted subcutaneous versus intraperitoneal bioscaffold seeded with hepatocyte-like cells: functional evaluation.

Amal Elham FaresHala GabrAsmaa Mohammed ShamsEldeenHaithem A M FarghaliMazen Mohamed Salem Mohamed RizkBassem Essam MahmoudAhmed Bakr Ahmed TammamAyman Magdy Ahmed MahmoudAlaa Abdulfattah Mahmoud SulimanMohamed Abdelhamid Ali AyyadSahar Hassan AhmedRokia Mohamad Hassan

Published in: Stem cell research & therapy (2021)

Implantation of decellularized bioscaffold seeded with trans-differentiated stem cells in rats was successful to establish production of FVIII. Subcutaneous implantation showed higher FVIII levels than intraperitoneal implantation.

Keyphrases

stem cells
extracellular matrix
liver injury
bone marrow
clinical evaluation