MUC5B promoter variant rs35705950, rare but significant susceptibility locus in rheumatoid arthritis-interstitial lung disease with usual interstitial pneumonia in Asian populations.
Young Bin JooSoo Min AhnSo-Young BangYoungho ParkSu Jin HongYoukyung LeeSoo Kyung ChoChan-Bum ChoiYoon-Kyoung SungTae Hwan KimJae-Bum JunDae Hyun YooSang-Cheol BaeHye-Soon LeePublished in: RMD open (2023)
variant rs35705950 is a rare but significant risk factor for Asian patients with RA-ILD with UIP, suggesting a sharing of the genetic background between Asian and Western populations.
Keyphrases
- interstitial lung disease
- rheumatoid arthritis
- systemic sclerosis
- idiopathic pulmonary fibrosis
- disease activity
- dna methylation
- gene expression
- south africa
- ankylosing spondylitis
- transcription factor
- genetic diversity
- genome wide
- social media
- healthcare
- systemic lupus erythematosus
- health information
- genome wide association study
- respiratory failure
- acute respiratory distress syndrome
- mechanical ventilation