Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2.

Huibi CaoJuntao MaiZhichang ZhouZhijie LiRongqi DuanJacqueline WattZiyan ChenRanmal Avinash BandaraMing LiSang Kyun AhnBetty PoonNatasha Christie-HolmesScott D Gray-OwenArinjay BanerjeeKaren MossmanRob KozakSamira MubarekaJames M RiniJim HuJun Liu

Published in: Cell & bioscience (2021)

Our approaches provide a powerful platform for constructing highly effective vaccines targeting SARS-CoV-2 and its emerging variants.

Keyphrases

sars cov
respiratory syndrome coronavirus
copy number
high fat diet induced
high throughput
cancer therapy
type diabetes
skeletal muscle
metabolic syndrome
gene expression
insulin resistance
dna methylation
respiratory tract