Factors predicting biochemical response and survival benefits following radioligand therapy with [177Lu]Lu-PSMA in metastatic castrate-resistant prostate cancer: a review.

Reyhaneh Manafi-FaridSara HarsiniBahare SaidiHojat AhmadzadehfarKen HerrmannAlberto BrigantiJochen WalzMohsen Beheshti

Published in: European journal of nuclear medicine and molecular imaging (2021)

Several studies have investigated a multitude of factors to detect those predicting response to [177Lu]Lu-PSMA RLT. The results wereinconsistent regarding some factors, and some were evaluated in only a few studies. Future prospective randomized trials are required to detect theindependent prognostic factors, and to further determine the clinical and survival benefits of [177Lu]Lu-PSMA RLT.

Keyphrases

pet ct
prostate cancer
prognostic factors
pet imaging
small cell lung cancer
squamous cell carcinoma
stem cells
radical prostatectomy
case control
bone marrow
atomic force microscopy