The detection of anti-dengue virus IgM in urine in participants enrolled in an acute febrile illness study in Puerto Rico.

Elba CaraballoB Katherine Poole-SmithKay M TomashekBrenda Torres-VelasquezLuisa I AlvaradoOlga D LorenziCarmen RamosJessica CarriónElizabeth Hunsperger

Published in: PLoS neglected tropical diseases (2020)

While detection of urine anti-DENV IgM lacked adequate diagnostic sensitivity, it is a highly specific marker for laboratory-positive dengue, and its presence early in the clinical course may distinguish those with more severe disease. Further assessment of urine anti-DENV IgM by DPO is warranted to determine its utility as an early diagnostic (and possibly prognostic) marker for dengue.

Keyphrases

dengue virus
zika virus
aedes aegypti
liver failure
loop mediated isothermal amplification
label free
real time pcr
drug induced
early onset
intensive care unit
urinary tract infection
chemotherapy induced