Relationship between circadian activity rhythms and fatigue in hospitalized children with CNS cancers receiving high-dose chemotherapy.

Valerie E RogersShijun ZhuBelinda N MandrellSonia Ancoli-IsraelLianqi LiuPamela S Hinds

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2019)

Participants demonstrated dysregulated CAR during hospitalization for HDCT. Greater dysregulation was associated with greater fatigue. Research on circadian dysregulation and its relationship to health-related outcomes in children with cancer, and interventions to support circadian rhythmicity, is urgently needed.

Keyphrases

high dose
young adults
sleep quality
low dose
papillary thyroid
physical activity
squamous cell carcinoma
childhood cancer
type diabetes
radiation therapy
depressive symptoms
adipose tissue
glycemic control