IRF4 and STAT3 activities are associated with the imbalanced differentiation of T-cells in responses to inhalable particulate matters.
Jinzhun WuDandan GeTaoling ZhongZuojia ChenYing ZhouLingyun HouXiaoliang LinJiaxu HongKuai LiuHui QiChaoying WangYulin ZhouCheng LiChuan WuShuiping WuZuguo LiuQiyuan LiPublished in: Respiratory research (2020)
Our study suggests the regulatory activities of IRF4 and STAT3 are associated with the Th17-mediated inflammatory responses to PM exposure in the respiratory tracts, which informs the biological background of the immunogenicity of particulate matters.