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Behaviors related to autism spectrum disorder in children with developmental language disorder and children with 22q11.2 deletion syndrome.

Iris SeltenTessel BoermaEmma EveraertEllen GerritsMichiel HoubenFrank WijnenJacob Vorstman
Published in: Autism & developmental language impairments (2023)
Our findings indicate that relations between early language impairment and other behavioral phenotypes may be more feasible to detect in a subgroup of children with a homogeneous etiology, than in a group of children with a heterogeneous etiology (such as children with DLD). Our results in 22q11DS reveal that receptive language is especially important in predicting the occurrence of ASD-related behaviors. Future research is needed to determine to what extent receptive language predicts the occurrence of ASD-related behaviors in children with DLD, especially among those children with DLD with the weakest receptive language. Clinically, screening for ASD-related behaviors in children with developmental language difficulties is recommended from a young age, especially among children with receptive language difficulties.
Keyphrases
  • autism spectrum disorder
  • young adults
  • risk assessment
  • intellectual disability
  • clinical trial
  • dna methylation
  • gene expression
  • single cell
  • phase iii
  • placebo controlled