Parental Age and Risk of Infant Leukaemia: A Pooled Analysis.

Erin L MarcotteTodd E DruleyKimberly J JohnsonMichaela RichardsonJulie von BehrenBeth A MuellerSusan CarozzaColleen McLaughlinEric J ChowPeggy ReynoldsLogan G Spector

Published in: Paediatric and perinatal epidemiology (2017)

This study demonstrates increased risk of infant ALL in relation to young paternal age. Given record linkage, there is little concern with recall or selection bias, although data are lacking on MLL gene status and other potentially important variables. Parent of origin effects, de novo mutations, and/or carcinogenic exposures may be involved in IL aetiology.

Keyphrases

genome wide
acute myeloid leukemia
big data
middle aged
gene expression
small molecule
human immunodeficiency virus
deep learning
data analysis