On the Analytic Characteristics of Commercial Acetaminophen Assays in the United States.

Khameinei AliWilliam ChiangJosh Jiaxing Wang

Published in: The journal of applied laboratory medicine (2022)

Commercially available APAP assays had good analytical precision with improvement over time. The failure of some manufacturers to validate precision near treatment thresholds is concerning. Newer APAP assays can measure a wider range of [APAP], which likely improves the risk stratification of overdose patients but also carries a risk of overdiagnosis when minuscule quantities are detected.

Keyphrases

high throughput
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
patient reported outcomes
mass spectrometry
combination therapy
liquid chromatography
smoking cessation