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Identification and characterization of smallest pore-forming protein in the cell wall of pathogenic Corynebacterium urealyticum DSM 7109.

Narges AbdaliFarhan YounasSamaneh MafakheriKarunakar R PothulaUlrich KleinekathöferAndreas TauchRoland Benz
Published in: BMC biochemistry (2018)
Biophysical characterization of the purified protein (PorACur) suggested indeed that cur_1714 is the gene coding for the pore-forming protein in C. urealyticum because the protein formed in lipid bilayer experiments the same pores as the detergent extract of whole cells. The study is the first report of a cell wall channel in the pathogenic C. urealyticum.
Keyphrases
  • cell wall
  • protein protein
  • amino acid
  • binding protein
  • oxidative stress
  • gene expression
  • dna methylation
  • copy number
  • small molecule
  • signaling pathway