The detection of isochromosome i(12p) in malignant germ cell tumours and tumours with somatic malignant transformation by the use of quantitative real-time polymerase chain reaction.
Alexander FichtnerAnnika RichterSimon FilmarNadine T GaisaStefan SchweyerHenning ReisDaniel NettersheimChristoph OingFabian A GayerAndreas LehaStefan KüfferPhilipp StröbelSilke KaulfußFelix BremmerPublished in: Histopathology (2020)
In summary, the qPCR assay presented here can help to identify, further characterise and assign a large proportion of histologically inconclusive malignancies to a GCT origin.