Intestine epithelial cell-derived extracellular vesicles alleviate inflammation induced by Clostridioides difficile TcdB through the activity of TGF-β1.
Shuangshuang WanGuangzhong SongHui HuYaqing XuPeng ZengShan LinJun YangJinqin JiangXiaojun SongYongneng LuoDazhi JinPublished in: Molecular & cellular toxicology (2022)
TcdB both in vitro and in vivo. Therefore, I-Evs might be potentially a novel endogenous candidate for effective treatment of CDI.