Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression.

Xiaoxu HuangZheng LiQiang ZhangWeizhi WangBowen LiLu WangZhipeng XuAiliang ZengXing ZhangXuan ZhangZhongyuan HeQiang LiGuangli SunSen WangQing LiLinjun WangLu ZhangHao XuZe-Kuan Xu

Published in: Molecular cancer (2019)

circAKT3 plays an important role in the resistance of GC to CDDP. Thus, our results highlight the potential of circAKT3 as a therapeutic target for GC patients receiving CDDP therapy.

Keyphrases

cell proliferation
long non coding rna
signaling pathway
gas chromatography
long noncoding rna
stem cells
mass spectrometry
risk assessment
cell therapy
smoking cessation
tandem mass spectrometry