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Sexually dimorphic patterns in maternal circulating microRNAs in pregnancies complicated by fetal growth restriction.

Bernadette C BakerSylvia LuiIsabel LorneAlexander E P HeazellKaren ForbesRebecca L Jones
Published in: Biology of sex differences (2021)
These studies have identified sexually dimorphic patterns for miRNAs in maternal serum in FGR. These miRNAs may have potential as non-invasive biomarkers for FGR and associated placental dysfunction. Further studies to determine if these miRNAs have potential functional roles in the placenta may provide greater understanding of the pathogenesis of placental dysfunction and the differing susceptibility of male and female fetuses to adverse in utero conditions.
Keyphrases
  • birth weight
  • gestational age
  • pregnancy outcomes
  • oxidative stress
  • case control
  • preterm birth
  • human health
  • pregnant women
  • climate change
  • body mass index