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Clinical Effectiveness and Safety of Chinese Herbal Medicine Compound Kushen Injection as an Add-On Treatment for Breast Cancer: A Systematic Review and Meta-Analysis.

Bao-Yong LaiAi-Jing ChuBo-Wen YuLi Yan JiaYing-Yi FanJian Ping LiuXiao-Hua Pei
Published in: Evidence-based complementary and alternative medicine : eCAM (2022)
Low certainty of evidence suggested that the combination of CKI and conventional chemotherapy appeared to improve ORR, DCR, and KPS score in breast cancer patients. Conclusions about PFS and OS could not be drawn due to lack of evidence. Additionally, CKI appeared to relieve the risk of ADRs in patients with breast cancer receiving chemotherapies. However, due to weak evidence, the findings should be further confirmed in large and rigorous trials.
Keyphrases
  • squamous cell carcinoma
  • combination therapy