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Variable selection for individualised treatment rules with discrete outcomes.

Zeyu BianErica E M MoodieSusan M ShortreedSylvie D LambertSahir Bhatnagar
Published in: Journal of the Royal Statistical Society. Series C, Applied statistics (2023)
An individualised treatment rule (ITR) is a decision rule that aims to improve individuals' health outcomes by recommending treatments according to subject-specific information. In observational studies, collected data may contain many variables that are irrelevant to treatment decisions. Including all variables in an ITR could yield low efficiency and a complicated treatment rule that is difficult to implement. Thus, selecting variables to improve the treatment rule is crucial. We propose a doubly robust variable selection method for ITRs, and show that it compares favourably with competing approaches. We illustrate the proposed method on data from an adaptive, web-based stress management tool.
Keyphrases
  • skeletal muscle
  • combination therapy
  • big data
  • weight loss
  • social media
  • deep learning
  • health information
  • heat stress
  • glycemic control