Ultrasensitive and affordable assay for early detection of primary liver cancer using plasma cell-free DNA fragmentomics.
Xiangyu ZhangZheng WangWanxiangfu TangXinyu WangRui LiuHua BaoXin ChenYulin WeiShuyu WuHairong BaoXue WuYang ShaoJia FanJian ZhouPublished in: Hepatology (Baltimore, Md.) (2022)
Our model, outperforming previous reports at a lower cost by solely using low-coverage WGS data, exhibits excellent clinical potential for ultrasensitive and affordable detection of PLC and its subtypes.
Keyphrases
- label free
- gold nanoparticles
- quantum dots
- molecularly imprinted
- electronic health record
- high throughput
- big data
- loop mediated isothermal amplification
- real time pcr
- human health
- healthcare
- emergency department
- adverse drug
- affordable care act
- machine learning
- risk assessment
- deep learning
- mass spectrometry
- high resolution
- artificial intelligence
- simultaneous determination
- liquid chromatography