Cytosporones Y and Z, new antifungal polyketides produced by the fungal strain Trichoderma sp. FKI-6626.
Haruki AzamiYoshihiro WatanabeHiroki KojimaYurika YoshidaSayaka BanKenichi NonakaTakashi YaguchiMasato IwatsukiPublished in: The Journal of antibiotics (2024)
Two new antifungal polyketides, named cytosporones Y (1) and Z (2), were discovered from the cultured broth of Trichoderma sp. FKI-6626. Their structures were elucidated by MS and NMR analysis. Both compounds exhibited antifungal activity against five Aspergillus species, the causative agents of aspergillosis.