Integrating genetic, transcriptional, and biological information provides insights into obesity.

Lan WangJeremiah PerezNancy Heard- CostaAudrey Y ChuRoby JoehanesPeter J MunsonDaniel LevyCaroline S FoxL Adrienne CupplesChing-Ti Liu

Published in: International journal of obesity (2005) (2018)

Our integrative analysis of genetic, transcriptional, and biological information provides a list of compelling candidates for further follow-up functional studies to uncover the biological mechanisms underlying obesity. These candidates highlight the value of examining CT-derived and central adiposity traits.

Keyphrases

insulin resistance
genome wide
metabolic syndrome
weight gain
weight loss
type diabetes
gene expression
high fat diet induced
transcription factor
computed tomography
copy number
health information
adipose tissue
magnetic resonance
skeletal muscle
oxidative stress
case control
pet ct