Increased PI3K pathway activity is associated with recurrent breast cancer in patients with low and intermediate 21-gene recurrence score.
Lawrence Hsu LinYvonne J W RozendaalVarshini VasudevarajaGuomiao ShenMargaret BlackDianne van StrijpSigi NeerkenPaul A van de WielGeorge JourPaolo CotziaFarbod DarvishianMatija SnuderlPublished in: Journal of clinical pathology (2024)
mutations, may play a role in the recurrence of early-stage breast cancer with low and intermediate 21-gene RS. Pathway analysis can help to identify high-risk patients in this setting.
Keyphrases
- early stage
- end stage renal disease
- ejection fraction
- copy number
- genome wide
- newly diagnosed
- chronic kidney disease
- free survival
- prognostic factors
- genome wide identification
- squamous cell carcinoma
- gene expression
- radiation therapy
- dna methylation
- transcription factor
- patient reported
- rectal cancer
- genome wide analysis
- breast cancer risk
- locally advanced