Damage of the lateral geniculate nucleus in MS: Assessing the missing node of the visual pathway.

Athina PapadopoulouLaura GaetanoArmanda PfisterAnna AltermattCharidimos TsagkasFelix MorencyAlexander U BrandtMartin HardmeierMallar M ChakravartyMaxime DescoteauxLudwig KapposTill SprengerStefano Magon

Published in: Neurology (2019)

LGN volume loss in MS indicates structural damage with potential functional relevance. Our results suggest both anterograde degeneration from the retina and retrograde degeneration from the OR lesions as underlying causes. LGN volume is a promising marker reflecting damage of the visual pathway in MS, with the advantage of individual measurement per patient on conventional MRI.

Keyphrases

mass spectrometry
multiple sclerosis
ms ms
oxidative stress
magnetic resonance imaging
case report
contrast enhanced
diabetic retinopathy
risk assessment
human health
climate change
optic nerve