Enterococcus faecalis OG1RF induces apoptosis in MG63 cells via caspase-3/-8/-9 without activation of caspase-1/GSDMD.

Yang LiCheng WenJialin ZhongJunqi LingQianzhou Jiang

Published in: Oral diseases (2021)

Enterococcus faecalis OG1RF induced both intrinsic and extrinsic MG63 cell apoptosis via caspase-3/-8/-9 activation but did not activate the pyroptotic pathway regulated by caspase-1/gasdermin D.

Keyphrases

induced apoptosis
cell death
endoplasmic reticulum stress
signaling pathway
cell cycle arrest
oxidative stress
cell proliferation