The B-Natural study-The outcome of immune tolerance induction therapy in patients with severe haemophilia B.

Jan AstermarkKatharina HolsteinYasmina L AbajasSusan KearneyStacy E Croteau Riana LiesnerEva FundingChristine L KemptonSuchitra AcharyaStefan LethagenPetra LeBeauJoel BowenErik Berntorp Amy D Shapiro

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2021)

Our data underscore the possibilities and difficulties of achieving tolerization in patients with HB with inhibitors. The type of mutation and complications appear to correlate with ITI outcome, but more accurate definitions of successful ITI are warranted.

Keyphrases

electronic health record
risk factors
big data
machine learning
artificial intelligence
drug induced